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mod header;
mod query;
mod record;
use futures::{stream, Stream};
use noodles_bgzf as bgzf;
use noodles_core::Region;
use noodles_csi::BinningIndex;
use noodles_vcf as vcf;
use tokio::io::{self, AsyncRead, AsyncReadExt, AsyncSeek};
use self::{header::read_header, query::query, record::read_record};
use crate::Record;
/// An async BCF reader.
///
/// # Examples
///
/// ```no_run
/// # use std::io;
/// #
/// # #[tokio::main]
/// # async fn main() -> io::Result<()> {
/// use futures::TryStreamExt;
/// use noodles_bcf as bcf;
/// use tokio::fs::File;
///
/// let mut reader = File::open("sample.bcf").await.map(bcf::r#async::io::Reader::new)?;
/// reader.read_header().await?;
///
/// let mut records = reader.records();
///
/// while let Some(record) = records.try_next().await? {
/// // ...
/// }
/// # Ok(())
/// # }
/// ```
pub struct Reader<R> {
inner: R,
}
impl<R> Reader<R>
where
R: AsyncRead + Unpin,
{
/// Returns a reference to the underlying reader.
///
/// # Examples
///
/// ```
/// use noodles_bcf as bcf;
/// let data = [];
/// let reader = bcf::r#async::io::Reader::from(&data[..]);
/// assert!(reader.get_ref().is_empty());
/// ```
pub fn get_ref(&self) -> &R {
&self.inner
}
/// Returns a mutable reference to the underlying reader.
///
/// # Examples
///
/// ```
/// use noodles_bcf as bcf;
/// let data = [];
/// let mut reader = bcf::r#async::io::Reader::from(&data[..]);
/// assert!(reader.get_mut().is_empty());
/// ```
pub fn get_mut(&mut self) -> &mut R {
&mut self.inner
}
/// Returns the underlying reader.
///
/// # Examples
///
/// ```
/// use noodles_bcf as bcf;
/// let data = [];
/// let reader = bcf::r#async::io::Reader::from(&data[..]);
/// assert!(reader.into_inner().is_empty());
/// ```
pub fn into_inner(self) -> R {
self.inner
}
/// Reads the VCF header.
///
/// The BCF magic number is checked, and the file format version is discarded.
///
/// The position of the stream is expected to be at the start.
///
/// # Examples
///
/// ```no_run
/// # use std::io;
/// #
/// # #[tokio::main]
/// # async fn main() -> io::Result<()> {
/// use noodles_bcf as bcf;
/// use tokio::fs::File;
///
/// let mut reader = File::open("sample.bcf").await.map(bcf::r#async::io::Reader::new)?;
/// let header = reader.read_header().await?;
/// # Ok(())
/// # }
/// ```
pub async fn read_header(&mut self) -> io::Result<vcf::Header> {
read_magic(&mut self.inner).await?;
read_format_version(&mut self.inner).await?;
read_header(&mut self.inner).await
}
/// Reads a single record without decoding (most of) its feilds.
///
/// The stream is expected to be directly after the header or at the start of another record.
///
/// It is more ergonomic to read records using a stream (see [`Self::records`]), but using
/// this method directly allows the reuse of a single [`Record`] buffer.
///
/// If successful, the record size is returned. If a record size of 0 is returned, the stream
/// reached EOF.
///
/// ```no_run
/// # use std::io;
/// #
/// # #[tokio::main]
/// # async fn main() -> io::Result<()> {
/// use noodles_bcf as bcf;
/// use tokio::fs::File;
///
/// let mut reader = File::open("sample.bcf").await.map(bcf::r#async::io::Reader::new)?;
/// reader.read_header().await?;
///
/// let mut record = bcf::Record::default();
/// reader.read_record(&mut record).await?;
/// # Ok(())
/// # }
/// ```
pub async fn read_record(&mut self, record: &mut Record) -> io::Result<usize> {
read_record(&mut self.inner, record).await
}
/// Returns an (async) stream over lazy records starting from the current (input) stream
/// position.
///
/// The (input) stream is expected to be directly after the header or at the start of another
/// record.
///
/// # Examples
///
/// ```no_run
/// # use std::io;
/// #
/// # #[tokio::main]
/// # async fn main() -> io::Result<()> {
/// use futures::TryStreamExt;
/// use noodles_bcf as bcf;
/// use tokio::fs::File;
///
/// let mut reader = File::open("sample.bcf").await.map(bcf::r#async::io::Reader::new)?;
/// reader.read_header().await?;
///
/// let mut records = reader.records();
///
/// while let Some(record) = records.try_next().await? {
/// // ...
/// }
/// # Ok(())
/// # }
/// ```
pub fn records(&mut self) -> impl Stream<Item = io::Result<Record>> + '_ {
Box::pin(stream::try_unfold(
(&mut self.inner, Record::default()),
|(mut reader, mut record)| async {
read_record(&mut reader, &mut record)
.await
.map(|n| match n {
0 => None,
_ => Some((record.clone(), (reader, record))),
})
},
))
}
}
impl<R> Reader<bgzf::AsyncReader<R>>
where
R: AsyncRead + Unpin,
{
/// Creates an async BCF reader.
///
/// # Examples
///
/// ```
/// use noodles_bcf as bcf;
/// let data = [];
/// let reader = bcf::r#async::io::Reader::new(&data[..]);
/// ```
pub fn new(inner: R) -> Self {
Self::from(bgzf::AsyncReader::new(inner))
}
}
impl<R> Reader<bgzf::AsyncReader<R>>
where
R: AsyncRead + AsyncSeek + Unpin,
{
/// Returns a stream over records that intersect the given region.
///
/// # Examples
///
/// ```no_run
/// # #[tokio::main]
/// # async fn main() -> Result<(), Box<dyn std::error::Error>> {
/// use futures::TryStreamExt;
/// use noodles_bcf as bcf;
/// use noodles_core::Region;
/// use noodles_csi as csi;
/// use tokio::fs::File;
///
/// let mut reader = File::open("sample.bcf").await.map(bcf::r#async::io::Reader::new)?;
/// let header = reader.read_header().await?;
///
/// let index = csi::r#async::read("sample.bcf.csi").await?;
/// let region = "sq0:8-13".parse()?;
/// let mut query = reader.query(&header, &index, ®ion)?;
///
/// while let Some(record) = query.try_next().await? {
/// // ...
/// }
/// # Ok(())
/// # }
/// ```
pub fn query<I>(
&mut self,
header: &vcf::Header,
index: &I,
region: &Region,
) -> io::Result<impl Stream<Item = io::Result<Record>> + '_>
where
I: BinningIndex,
{
use crate::io::reader::resolve_region;
let reference_sequence_id = resolve_region(header.string_maps().contigs(), region)?;
let chunks = index.query(reference_sequence_id, region.interval())?;
Ok(query(
self,
chunks,
reference_sequence_id,
region.interval(),
))
}
}
impl<R> From<R> for Reader<R> {
fn from(inner: R) -> Self {
Self { inner }
}
}
async fn read_magic<R>(reader: &mut R) -> io::Result<()>
where
R: AsyncRead + Unpin,
{
use crate::MAGIC_NUMBER;
let mut magic = [0; 3];
reader.read_exact(&mut magic).await?;
if magic == MAGIC_NUMBER {
Ok(())
} else {
Err(io::Error::new(
io::ErrorKind::InvalidData,
"invalid BCF header",
))
}
}
async fn read_format_version<R>(reader: &mut R) -> io::Result<(u8, u8)>
where
R: AsyncRead + Unpin,
{
let major_version = reader.read_u8().await?;
let minor_version = reader.read_u8().await?;
Ok((major_version, minor_version))
}
#[cfg(test)]
mod tests {
use super::*;
#[tokio::test]
async fn test_read_magic() {
let data = b"BCF";
let mut reader = &data[..];
assert!(read_magic(&mut reader).await.is_ok());
let data = [];
let mut reader = &data[..];
assert!(matches!(
read_magic(&mut reader).await,
Err(ref e) if e.kind() == io::ErrorKind::UnexpectedEof
));
let data = b"BAM";
let mut reader = &data[..];
assert!(matches!(
read_magic(&mut reader).await,
Err(ref e) if e.kind() == io::ErrorKind::InvalidData
));
}
#[tokio::test]
async fn test_read_format_version() -> io::Result<()> {
let data = [0x02, 0x01];
let mut reader = &data[..];
assert_eq!(read_format_version(&mut reader).await?, (2, 1));
Ok(())
}
}